Primary Identifier | MGI:6771469 | Allele Type | Endonuclease-mediated |
Attribute String | Null/knockout | Gene | Cfap206 |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR-targeting against exons 3 through 11 duplicated an A nucleotide and generated a frameshift variant (c.1430dupA; p.Asn477LysfsTer15; NM_001031743.2). Western blot analysis confirmed the complete absence of protein expression in testicular tissue from homozygous mutant mice. |