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Allele : Gabbr1<tm4Bet> gamma-aminobutyric acid type B receptor subunit 1; targeted mutation 4, Bernhard Bettler

Primary Identifier  MGI:3665433 Allele Type  Targeted
Attribute String  Modified isoform(s) Gene  Gabbr1
Transmission  Germline Strain of Origin  BALB/c
Is Recombinase  false Is Wild Type  false
molecularNote  The start codon for the B1b isoform of Gabbr1 was converted into a stop codon to prevent translation of the B1b isoform. A floxed neomycin cassette was inserted in the introns between exons 5a and 1b. The neomycin cassette was removed by crossing with mice expressing Cre-recombinase under the control of the cytomegalus virus promoter. Northern blot analysis confirmed absence of the B1b isoform.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • 1b<->,
  • GABAB1b<->,
  • GABAB(1b)<->,
  • GABAB(1b)<->,
  • 1b<->,
  • GB1b<->,
  • GABAB1b<->,
  • GB1b<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

20 Publication categories

Trail: Allele