Primary Identifier | MGI:6406268 | Allele Type | Targeted |
Attribute String | Reporter | Gene | Drd2 |
Transmission | Germline | Strain of Origin | C57BL/6N |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A superecliptic pHluorin (SpH) with a human prolactin hormone signal sequence was introduced to exon 2 of the mouse Drd2 gene, enabling the expression of a fused GFP-D2R protein. A loxP-flanked PGK-neomycin cassette was placed in intron 2. Cre-mediated recombination removed the floxed neo cassette. |