Primary Identifier | MGI:2680042 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Slc12a6 |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A cassette containing lacZ and neo replaced a 2.2 kb genomic fragment encompassing 95 bp of exon 3 and all of exon 4. While normal protein was undetected by Western blot analysis of various tissues obtained from homozygous mutant mice, expression of a hybrid protein consisting of the endogenous N-terminal fused to lacZ was detected. |