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Allele : Slc12a6<tm1Tjj> solute carrier family 12, member 6; targeted mutation 1, Thomas J Jentsch

Primary Identifier  MGI:2680042 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Slc12a6
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A cassette containing lacZ and neo replaced a 2.2 kb genomic fragment encompassing 95 bp of exon 3 and all of exon 4. While normal protein was undetected by Western blot analysis of various tissues obtained from homozygous mutant mice, expression of a hybrid protein consisting of the endogenous N-terminal fused to lacZ was detected.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • Kcc3<->,
  • Kcc3<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

9 Publication categories

Trail: Allele