Primary Identifier | MGI:2447142 | Allele Type | Targeted |
Attribute String | Null/knockout, Reporter | Gene | Tshr |
Transmission | Germline | Strain of Origin | 129S1/Sv-Oca2<+> Tyr<+> Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The endogenous locus was disrupted by an EGFP-neo cassette inserted by homologous recombination. The absence of normal transcript and protein in homozygous mutant mice was demonstrated by RT-PCR and Western blot analyses. GFP expression was confirmed at both the transcript and protein levels. |