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Allele : Pdgfb<tm2Cbet> platelet derived growth factor, B polypeptide; targeted mutation 2, Christer Betsholtz
Primary Identifier  MGI:2385913 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Pdgfb
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
description  Mutants in J:89186 provide a model for microvascular changes that bear striking resemblance to diabetic microangiopathy.
molecularNote  Exon 4 was floxed by insertion of a loxP-PGK-neo-loxP cassette into intron 3 and insertion of a loxP site into intron 4 via homologous recombination.
  • mutations:
  • Insertion
  • synonyms:
  • PDGF-B<flox>,
  • PDGF-B<flox>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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