Primary Identifier | MGI:3613572 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Rap1gds1 |
Transmission | Germline | Strain of Origin | 129X1/SvJ |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A neomycin resistance cassette replaced 1.7 kb of genomic sequence including the 3' half of exon 5, and exons 6 and 7, removing the portion of the gene that encodes amino acids 212-343. Western blot analysis using a carboxy terminal specific antibody did not detect protein in brain tissue from homozygous mutant mice. RT-PCR analysis of brain did not detect expression in homozygous mutant mice. |