| Primary Identifier | MGI:6728538 | Allele Type | Targeted |
| Attribute String | Conditional ready, Null/knockout, Recombinase | Gene | Pdgfra |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | The targeting cassette consisting of a SA.lox.Neo/Stop.lox-PDGFRaK.T2A.Flp cassette replaced the exons 2-4 of the endogenous Pdgfra gene. The PDGFRaK is a mouse Pdgfra gene cDNA with a point mutation (D842V) renders it constitutively active. Cre-mediated recombination is required to achieve expression of the constitutively active Pdgfra gene with a point mutation (D842V) and the flpo recombinase. In cre naive state it is a null allele. |
