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Allele : Tg(tetO/Prnp-MAPT*P301L,-luc)Y74Dbo transgene insertion Y74, David R Borchelt
Primary Identifier  MGI:5615836 Allele Type  Transgenic
Attribute String  Humanized sequence, Inducible, Reporter Gene  Tg(tetO/Prnp-MAPT*P301L,-luc)Y74Dbo
Strain of Origin  FVB/NJ Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  The transgenic construct includes a Tet-responsive element (TRE) and exons 1-2 (non-coding) from the mouse prion protein upstream of a Tau-Ubiquitin-Luciferase (TUL) cDNA sequence, followed by mouse prion protein exon 3 (non-coding) and polyadenylation signal. The TUL cDNA sequence encodes a mutant human tau-P301L with C-terminal ubiquitin, followed by a luciferase gene.
  • mutations:
  • Insertion
  • synonyms:
  • TUL-Y74,
  • TUL-Y74
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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