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Allele : Met<tm2.1Ics> met proto-oncogene; targeted mutation 2.1, Mouse Clinical Institute

Primary Identifier  MGI:7738838 Allele Type  Targeted
Gene  Met Transmission  Germline
Strain of Origin  C57BL/6NCrl Is Recombinase  false
Is Wild Type  false
molecularNote  A loxP site flanked neomycin resistance gene cassette was inserted into intron 21 (in ENSMUST00000115443) and a c.4120G>A mutation was created in exon 22, changing aspartic acid codon 1374 (GAT) to asparagine (AAT) (p.D1374N) in the C-terminal caspase site of the encoded peptide. The neo cassette was removed through subsequent Cre-mediated recombination.
  • mutations:
  • Single point mutation,
  • Insertion
  • synonyms:
  • MET D1374N,
  • MET D1374N
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele