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Allele : Cdk4<tm1.1Bbd> cyclin-dependent kinase 4; targeted mutation 1.1, Mariano Barbacid

Primary Identifier  MGI:2154521 Allele Type  Targeted
Gene  Cdk4 Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
description  Phenotypic Similarity to Human Syndrome: Melanoma (J:189221)
molecularNote  This allele is a derivative of Cdk4tm1Bbd in which the neomycin resistance cassette was deleted via Cre-mediated recombination in the germ line. These mice express comparable levels of mutant protein to wild-type levels.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
  • synonyms:
  • Cdk4<R24C>,
  • Cdk4<R>,
  • Cdk4<R>,
  • Cdk4<R24C>,
  • Cdk4 R24C,
  • Cdk4 R24C
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Human diseases

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

Trail: Allele

50 Publication categories

Trail: Allele