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Allele : Trmt10a<tm1e(EUCOMM)Wtsi> tRNA methyltransferase 10A; targeted mutation 1e, Wellcome Trust Sanger Institute

Primary Identifier  MGI:4434214 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Trmt10a
Transmission  Cell Line Strain of Origin  C57BL/6N
Is Recombinase  false Is Wild Type  false
Project Collection  EUCOMM
molecularNote  The L1L2_Bact_P cassette was inserted at position 138147913 of Chromosome 3 upstream of the critical exon(s) (Build GRCm38). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. Insertion of this cassette creates a reporter knockout mouse. Cre expression will remove the neomycin selection cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Human diseases

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

3 Publication categories