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Allele : Nphs1<tm1Ktry> nephrosis 1, nephrin; targeted mutation 1, Karl Tryggvason

Primary Identifier  MGI:2386182 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Nphs1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A cassette containing lacZ and neo was inserted in frame into exon 1. While expression of beta-galactosidase was driven by the endogenous promoter, neither endogenous transcript nor protein was detected in homozygous mice by RT-PCR and Western blot analyses.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Human diseases

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

6 Publication categories

Trail: Allele