| Type | MGI:General | Description | mice are protected from extensive pyramidal cell loss in the hippocampal CA3 region resulting from kainate injection the mice are also protected from neuroinflammation induced by kainate the neuronal damage score of this brain region is half that of wild-type mice injected with the same amount of kainate no injury is detectable in the CA1 region and in the granule cell layer of the dentate gyrus while in wild-type mice injury is sometimes observed |