| Type | MGI:General | Description | starting at 3 months of age, heterozygous females show a 33% reduction in litter size relative to wild-type littermates litter size is further reduced at 7 months (54% less), and by 12 months heterozygous females deliver an average of only 0.5 ± 0.3 offspring that die within 18-48 hrs after birth while 73% of wild-type controls continue to produce viable offspring |
