| Type | MGI:General | Description | mice infected with a sublethal dose of mouse-adapted SARS-CoV MA15 continue to lose weight through day 7 postinfection, showing more weight loss than wild-type controls at 5-7 days post infection (dpi), decreased locomotion, hunched posture, and labored breathing SARS-CoV MA15-infected mice exhibit cuffing of inflammatory cells around the large airways and vasculature and mild interstitial membrane thickening and a few inflammatory cells in the alveolar spaces at 4 dpi, with moderate level of disease in the parenchyma by 7 dpi |
