| Type | MGI:General | Description | at P0, RV cardiomyocytes appear rounded (spherically shaped) and exhibit defective polarity with loss of long F-actin filaments; active beta-catenin staining at cell-cell junctions is decreased at E13.5, suggesting reduced cell adhesion at E12.5 and E15.5, expression of SCRIB (scribble planar cell polarity protein) is almost absent in the RV and interventricular septum junction, supporting a failure of cardiomyocytes to undergo polarization in culture, neonatal cardiomyocytes show disrupted actin organization, absence of distinct cell projections, and a significantly shorter long-axis length; >40% of cardiomyocytes are rounded, whereas control cardiomyocytes are elongated |
