| Type | MGI:General | Description | homozygotes display improper activation of B cells, as shown by an increased proportion of IgD-IgMlow B cells in the germinal center of lymph nodes at 10 weeks of age, mutant B cells isolated from blood and all secondary lymphoid organs express higher levels of MHC II molecules than wild-type B cells at 3 weeks of age, homozygotes harbor activated B cells (with increased expression levels of MHC II) only in peripheral lymph nodes but not in blood or spleen |
