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Comment :

Type  MGI:General Description  homozygotes display a congenital 30% reduction in Ca2+ channel current density, a slower inactivation rate, and a reduced dihydropyridine (DHP)-sensitive current in aortic smooth muscle cells in response to KCl, homozygotes show reduced responsiveness to diltiazem (an L-type calcium channel blocker) in the global [Ca2+]i, with no significant changes in local Ca2+ sparks in mesenteric arteries