| Type | MGI:General | Description | homozygotes display a congenital 30% reduction in Ca2+ channel current density, a slower inactivation rate, and a reduced dihydropyridine (DHP)-sensitive current in aortic smooth muscle cells in response to KCl, homozygotes show reduced responsiveness to diltiazem (an L-type calcium channel blocker) in the global [Ca2+]i, with no significant changes in local Ca2+ sparks in mesenteric arteries |