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Comment :

Type  MGI:General Description  when doxycycline induction on double-mutants is performed from postnatal day 8 to P15 by introduction into drinking water, 4-, 6-, and 10-week old mice form multiple osteochondromas (in knees and ribs) with 100% penetrance when induction with doxycycline is achieved by intraperitoneal injection to lactating dams on P8, 100% of offspring exhibit osteochondromas