| Type | MGI:General | Description | at 10 weeks of age, nonfasting homozygotes exhibit significantly lower serum insulin levels than wild-type mice after overnight fasting (i.e., before glucose injection), most homozygotes display serum insulin levels less than 0.1 ng/ml relative to 0.24 ± 0.06 ng/ml in wild-type mice at 30 minutes after glucose injection, mutant serum insulin levels remain below 0.1 ng/ml, whereas wild-type serum insulin levels increase by 2-fold |
