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Comment :

Type  MGI:General Description  in vitro, less than 50% of primary cardiomyocytes isolated from E14.5 hearts show a clear striated pattern of alpha-actinin labeling versus >80% in wild-type controls; no clear striated pattern is seen for F-actin labeling E14.5 cardiomyocytes, which lack a clear striated pattern, show an abnormal pattern of alpha-actinin staining, indicating abnormal Z line organization