| Type | MGI:General | Description | aberrant, disorganized granules as well as decreased granule numbers are observed in these mice virtually all Paneth cells have lysozyme localized throughout the cell instead of being discretely packaged within vesicles Paneth cells also have degenerating mitochondria, loss of granules and the frequent absence of apical microvilli adjacent crypt lumen often contains intact Paneth granules and cytoplasm, which is a phenomenon not observed in wild-type controls |
