| Type | MGI:General | Description | fructose levels in feces are 2-fold higher in mice fed a high fructose diet, indicating development of fructose intolerance plasma alanine transaminase, aspartate transaminase, and lactate dehydrogenase, indicators of liver injury, are not increased in mutant mice fed a high fructose diet unlike in wild-type mice that show an increase in their levels, indicating resistance to liver damage by high fructose diet due to impaired fructose absorption on the high fructose diet, lactate levels in the intestine are not increased as in wild-type mice and lactate levels in the liver are decreased in mutants indicating impaired fructose conversion into lactate in the intestine but not the liver |
