| Type | MGI:General | Description | thymic T cell subsets are normal with the exception of high expression of the CD45 isoforms RA and RC that are not expressed on wild-type thymoctes naïve CD44lo T cells fail to accumulate in the periphery as the mice age CD44hi memory T cells compensate for peripheral T cell lymphopenia by homeostatic proliferation leading to an increase in the percentage of memory CD4 T cells |