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Type  MGI:General Description  corneal endothelial cell density is lower at 40 weeks, but not 10 weeks, of age increase in corneal endothelial cell area in 40 week old mice mild corneal endothelial cell swelling is seen at 10 weeks of age which progresses with age and leads to increasing distortion of the hexagonal morphology of the cells destruction of the corneal endothelial cell membrane is seen at 90 weeks of age intracellular vacuolization of the corneal endothelial cell that worsens with increasing age deposition of amorphous material and disorganization of collagen fibrils in the stroma of corneal endothelial cells