| Type | MGI:General | Description | accumulation of white blood cells invading into islets CD8+ T and CD4+ T cells infiltrate into the islets by 12 weeks of age MCHII+CD11b+CD11c- macrophages, CD3e+ T cells and CD19+ B cells are increased in the pancreases of mutants macrophage infiltration into the pancreas by 14 weeks of age and these macrophages express high levels of proinflammatory cytokines |