| Type | MGI:General | Description | at E17.5 in offspring from homozygous crosses, the stratum corneum is absent or if present is only 1 cell layer thick and lacks the normal membrane localization of polar lipids and organization of lamellar body-derived material into lamellar structures however, at birth a normal multilayered stratum corneum is present supplementation of homozygous females with corticosterone during pregnancy rescues the delay in stratum corneum development in homozygous pups |