| Type | MGI:General | Description | disruption of blood-brain barrier and blood-spinal cord barrier in areas of motor neuron degeneration in the brainstem, cervical and lumbar spinal cord pericytes under the capillary basement membrane intracellular edema, endoplasmic reticulum swelling and formation of numerous large vacuoles in capillary endothelial cells cytoplasm multiple layers of endothelial cells separated by sheets of basement membrane material |
