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Comment :

Type  MGI:General Description  the increase in temperature seen 20 minutes after exposure to 1 ug/kg LPS is blunted and later increases do not occur treatment with 10 ug/kg results in a blunted increase in temperature followed by a hypothermic response treatment with 100 ug/kg results in a blunted increase in temperature followed by a profound hypothermic response treatment with 1 mg/kg produces a more intense triphasic hypothermia rather than the biphasic hypothermic response seen in wild-type controls