| Type | MGI:General | Description | bone marrow cultured with IL-7 over a 6 day period to promote selective expansion of pre-B cells exhibits an approximate 7-fold enhancement in the frequency of activated immature mutant B cells relative to immature wild-type B cells gating on activated B cells shows that immature mutant B cells proliferate to a much greater extent than immature wild-type B cells these experiments show that upon BCR engagement, immature B cells are activated and proliferate rather than being inhibited and undergoing anergy |
