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Comment :

Type  MGI:General Description  in response to i.p. injection of IL-1beta (1.0 µg/mouse) and LPS (2.5 µg/mouse), male homozygotes show an attenuated reduction in social interaction relative to wild-type males notably, i.c.v. administration of IL-1beta and LPS depresses social exploration only in wild-type mice, whereas mutants remain unaffected