| Type | MGI:General | Description | at E17.5, homozygotes display no vessel invasion into cartilage, in spite of abundant vascularization in the perichondrium and the surrounding tissue absence of cartilage angiogenesis is associated with lack of VEGF upregulation in hypertrophic chondrocytes, and no upregulation of the expression of VEGF receptors in perichondrial endothelial cells |