| Type | MGI:General | Description | benzo[a]pyrene (BaP)-treated mice exhibit moderate toxicity (weight loss, decreased spleen and thymus weight, increased liver weight, increased serum alanine and aspartate transaminase levels, decreased hematocrit and hemoglobin, increased methemoglobin, increased neutrophils, and decreased lymphocytes) compared with similarly treated wild-type mice BaP-toxicity is more severe than in similarly treated Cyp1a1tm4.1Dwn homozygotes |
