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Comment :

Type  MGI:General Description  females exhibit enhanced T-cell activation splenic T cells from 3 month old females show a higher proportion of effector/memory cells (CD44hiCD62Llo) compared with wild-type mice females exhibit more IFN-gamma-producing CD4+ T cells and more TNF-alpha-producing CD8+ T cells in splenocytes the frequency of proinflammatory cytokine-producing CD4+ T cells is higher in the pancreatic lymph nodes of mutant mice compared with wild-type mice