| Type | MGI:General | Description | at P1 and P28, viable homozygotes of an isogenic or mixed genetic background exhibit a ~30% increase in the number of cardiac myocytes; however, no cardiomyocyte hypertrophy is noted up to 4 weeks of age postnatal cardiac hypercellularity is in stark contrast to the hypocellular cardiac phenotype of embryos that die at E11.5, suggesting a finely tuned mechanism that governs the balance between cardiomyocyte proliferation and differentiation |
