| Type | MGI:General | Description | prolonged activation by KCl depolarisation of intact bladder preparations from homozygous mutant neonates indicates absence of the initial transient state of of high force generation and maximal shortening velocity (phase 1) in contrast, phase 2, a subsequent sustained state characterized by low force generation and maximal shortening velocity remains normal, suggesting that in neonatal smooth muscle phase 1 is generated by recruitment of smooth-muscle myosin heavy chain (MHC), whereas phase 2 can be generated by activation of non-muscle MHC |
