| Type | MGI:General | Description | apical membrane-enriched brush border membrane vesicles (BBMVs) isolated from the kidney cortex of homozygous mutant mice show a dramatic reduction in [3H] glycine uptake activity at substrate concentrations less than 1 mM close analysis of the uptake kinetics by the Eadie-Hofstee method shows that the high-affinity component of renal glycine reabsorption is absent in mutant mice |