| Type | MGI:General | Description | following pI-pC treatment, saw an increase in Mac-1+/Gr-1+ myeloid cells in bone marrow, indicating myeloid hyperplasia 3 weeks following pI-pC treatment, mutants had an average three-fold increase in granulocyte/macrophage progenitors (GMPs) and a three-fold reduction in the number of common lymphoid progenitors (CLPs) in the bone marrow enhanced self-renewal/proliferation of myeloid progenitors (hematopoietic stem cells (HSCs), GMPs and common myeloid progenitors (CMPs)) as indicated by their ability to generate colonies upon serial replating |
