| Type | MGI:General | Description | raised lesions are observed in large intestine at 3 and 6 weeks affected areas display mucosal thickening, characterized by dysplastic epithelial cells with increased nuclear to cytoplasmic ratios and increased mitotic figures typical of microadenomas by 6 weeks, microadenomas and adenomas are multifocally distributed throughout distal and proximal colon lesions exhibit cytoplasmic and nuclear accumulation of beta-catenin in dysplastic epithelial cells; proliferation of these cells is increased, and extends beyond the crypt base |