| Type | MGI:General | Description | at 2.5 months of age, Sertoli cells exhibit vacuolation and accumulation of large lipid droplets Sertoli cell vacuoles are surrounded by membrane and occasionally contain multivesicular body-like structures vacuolar membranes are often lined by actin filament bundles with endoplasmic reticulum cisternae located beneath them, suggesting germ cell loss number of GATA4-immunoreactive Sertoli cells declines dramatically between 4 and 6 months of age, whereas the number of GATA1-and AR-immunoreactive Sertoli cells remains constant |
