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Comment :

Type  MGI:General Description  both the actin and microtubule cytoskeleton appear disorganized in Sertoli cells from P15, as shown by irregular arrangement and aberrant assembly of actin filaments and microtubules, respectively vimentin (a marker of the intrinsic cytoskeleton of SCs) fails to form apical extensions at P15 while its directional polarity is lost vimentin distribution appears disordered and its expression is completely lost in some tubules at 2 months of age