| Type | MGI:General | Description | fibrosis at 12 weeks disorganized sarcomeres in the diaphragm at 6 months, including sarcomeric Z-line streaming, the insertion of an additional sarcomere, and myofibrillar disorganization with focal loss of cross-striation diaphragm muscle exhibits filament disruption, small rod bodies and vacuoles and central nuclei irreversible aggregation of filamin C and sarcoglycans reduced muscle mass with reduced muscle weight at 12 weeks |
