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Comment :

Type  MGI:General Description  most mice die between 4 and 6 months of age more than 50% of females survive to 5 months of age, approximately 1 month longer than males, indicating better survival for females treatment with rapamycin from P10 to P60 improves survival, with female rapamycin-treated mice having a median survival of about 7 months and male rapamycin-treated mice 6 months enhanced rapamycin treatment (extended duration) improves lifespan even more to a median survival of about 8 months