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Comment :

Type  MGI:General Description  whole-cell patch-clamp recordings show an approximate 5-fold higher basal potassium conductance in acutely isolated smooth muscle cells the effect of pinacidil, the K(ATP) channel opener, is blunted in vascular smooth muscle cells (does not provoke increase in conductance) and subsequent application of the K(ATP) channel inhibitor, glibenclamide, is less effective