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Comment :

Type  MGI:General Description  carnitine-independent CPT2-coupled beta-oxidation of long-chain acylcarnitines as well as the pyruvate (N) or pyruvate and succinate (NS) pathway-linked respiration rate in the OXPHOS state is 24-46% higher in cardiac fibers, indicating that mitochondrial bioenergetics related to pyruvate and fatty acid metabolism are stimulated 25% lower lactate and succinate concentrations in the plasma, indicating that mitochondrial metabolism of lactate/pyruvate and the Krebs cycle are increased in response to the lower long-chain acylcarnitine levels