| First Author | Ikeda M | Year | 1995 |
| Journal | Biochem Biophys Res Commun | Volume | 207 |
| Issue | 2 | Pages | 800-6 |
| PubMed ID | 7864875 | Mgi Jnum | J:22968 |
| Mgi Id | MGI:70836 | Doi | 10.1006/bbrc.1995.1257 |
| Citation | Ikeda M, et al. (1995) Detection of messenger RNA for gonadotropin-releasing hormone (GnRH) but not for GnRH receptors in mouse mammary glands. Biochem Biophys Res Commun 207(2):800-6 |
| abstractText | While gonadotropin-releasing hormone (GnRH), GnRH-like, or GnRH receptor (GnRH-R) have been reported to exist in several tissues other than brain or anterior pituitary, there is no report concerning GnRH or GnRH-R gene expression in the normal mammary gland. In order to define the production of GnRH as well as GnRH-R in the mammary gland at the molecular level we examined their gene expression in various functional stages of the mouse mammary gland using the reverse transcriptase-polymerase chain reaction (RT-PCR). GnRH mRNA transcripts were found in mouse mammary glands of mid-pregnant, lactating, and 3, 6, 9 days post-lactational mice, whereas GnRH-R mRNA transcripts were not detected in mammary glands of any functional stage. These results suggest a possible biological role of GnRH in mammary gland. |
