| First Author | Zaia A | Year | 2000 |
| Journal | Mech Ageing Dev | Volume | 113 |
| Issue | 3 | Pages | 227-32 |
| PubMed ID | 10714941 | Mgi Jnum | J:60414 |
| Mgi Id | MGI:1353260 | Doi | 10.1016/s0047-6374(99)00118-9 |
| Citation | Zaia A, et al. (2000) Insulin receptors in the brain cortex of aging mice. Mech Ageing Dev 113(3):227-32 |
| abstractText | The aim of the present study was to analyze whether aging also affects central insulin receptors in brain cortex as it does in whole brain of BALB/c-nu mice. Results showed statistically significant decrease of number and increase of affinity of insulin high affinity binding sites in old animals. As a consequence, central insulin actions, among which neuromodulation of monoaminergic system, can result altered during aging. |
