First Author | Ylönen A | Year | 1999 |
Journal | Eur J Biochem | Volume | 266 |
Issue | 3 | Pages | 1066-72 |
PubMed ID | 10583403 | Mgi Jnum | J:59012 |
Mgi Id | MGI:1350778 | Doi | 10.1046/j.1432-1327.1999.00950.x |
Citation | Ylonen A, et al. (1999) Atlantic salmon (Salmo salar L.) skin contains a novel kininogen and another cysteine proteinase inhibitor. Eur J Biochem 266(3):1066-72 |
abstractText | We describe the purification and characterization of two novel cysteine proteinase inhibitors found in Atlantic salmon skin. One of these, salmon kininogen, has a molecular mass of 52 kDa as determined by matrix-assisted laser desorption/ionization time-of-flight MS, is multiply charged with pI values of 4.0, 4.2 and 4.6 and shows homology to kininogens including the bradykinin motif. The other, salarin, has a molecular weight of 43 kDa, a pI of 5.1 and shows weak homology to cysteine proteinases. Both proteins are N- and O-glycosylated and inhibit papain and ficin but not trypsin. |