| First Author | Novak R | Year | 1980 |
| Journal | Science | Volume | 207 |
| Issue | 4426 | Pages | 86-7 |
| PubMed ID | 7350646 | Mgi Jnum | J:6247 |
| Mgi Id | MGI:54724 | Doi | 10.1126/science.7350646 |
| Citation | Novak R, et al. (1980) Gene affecting superoxide dismutase activity linked to the histocompatibility complex in H-2 congenic mice. Science 207(4426):86-7 |
| abstractText | The activity of cyanide-sensitive, Cu-Zn superoxide dismutase (SOD) was studied in liver sytosols from H-2 congenic strains of mice. Higher SOD activity was found in livers of mice having H-2b/A.BY, B10, and C3H.SW/haplotypes than in those of H-2a, H-2k and H-2d haplotypes. Segregation studies supported these correlations. In H-2 recombinant strains of mice, the genes influencing the liver SOD activity occur, as ascertained by mapping techniques, at or near the H-2d region of the major histocompatibility complex. |
